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Market News: Doctors say Brazilian President Lula is fully capable of signing official documents. The gap between Italian and German government bond yields widened to 111 basis points, the highest level in a week.

American stock index futures maintained a downward trend, with S&P 500 E-MINI futures down 0.3%, Nasdaq futures down 0.6% and Dow Jones futures down 0.1%.Market News: Japan and the United States are looking for technologies to counter the threats of biology and misinformation.Market News: Ibrahim Karin, Director of Turkish Intelligence Agency, has arrived in the Syrian capital.

The Dow opened up 0.04%, the S&P 500 fell 0.2%, the Nasdaq fell 0.4% and Adobe fell 10.4%, and the fiscal year performance guidance fell short of expectations. General Dynamics fell 2.8% and was bearish by institutions. Uber rose by 3.5%, and its volume dropped by nearly 6% yesterday. CFO said that the mobile business will grow steadily. Jinshan Cloud rose 2.5%, and UBS sharply raised its target price to $12.5.European Central Bank President Lagarde: As we gradually approach the neutral interest rate, we will further discuss its related issues. The neutral interest rate may be slightly higher than before. We will discuss the neutral interest rate in due course.According to statistics, on December 12th, as of press time, five A-share listed companies including Alaide, Zhongzhong Technology, Yiwang Yichuang, Crystal Optoelectronics and Decai Co., Ltd. disclosed their holdings.